Download PDF by Bradley K. Taylor, David P. Finn: Behavioral Neurobiology of Chronic Pain

By Bradley K. Taylor, David P. Finn

ISBN-10: 3662450933

ISBN-13: 9783662450932

ISBN-10: 3662450941

ISBN-13: 9783662450949

Pain is the most typical cause humans search clinical support. The remedy of power soreness is an immense unmet scientific desire and its influence on health and wellbeing, healthiness, society and the economic system is tremendous. discomfort is an integrative, whole-systems (patho)physiological phenomenon and behavioural neuroscience performs a key position in advancing our realizing of ache. This quantity brings jointly a sequence of authoritative chapters written by means of prime specialists in preclinical and scientific facets of ache neurobiology. Behavioural methods to the learn of continual or persistent discomfort in animal versions or people are on the center of the quantity, however the anatomical, physiological, neurochemical and molecular mechanisms that underpin behavioural changes also are emphasised. ​

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Extra info for Behavioral Neurobiology of Chronic Pain

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Health Qual Life Outcomes 1:79 Weiser TG, Regenbogen SE, Thompson KD, Haynes AB, Lipsitz SR, Berry WR et al (2008) An estimation of the global volume of surgery: a modelling strategy based on available data. Lancet 372(9633):139–144 Werner MU, Kehlet H (2010) Characterization of persistent postoperative pain by quantitative sensory testing. Eur J Pain Supplements 4:203-207 Werner MU, Kongsgaard UE (2014) Defining persistent post-surgical pain: is an update required?. Br J Anaesth (E-preprint) Persistent Postsurgical Pain 29 Werner MU, Mjobo HN, Nielsen PR, Rudin A (2010) Prediction of postoperative pain: a systematic review of predictive experimental pain studies.

2004). Facial Expression. Arguably, the most innovative approach to readouts reflecting pain in laboratory animals is the analysis of facial expression using grimace scales (Langford et al. 2010). These were inspired by scales used in Behavioral Pharmacology of Pain 41 nonverbal humans (Williams 2002). Observers tend to focus on the face, which may be an advantage in grimace analyses but a challenge in behavioral paradigms that involve other, or multiple body parts (Leach et al. 2011). The mouse grimace scale (Langford et al.

Clin J Pain 28(2):136–142 Wildgaard K, Ringsted TK, Hansen HJ, Petersen RH, Werner MU, Kehlet H (2012b) Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy. Br J Anaesth 108(1):126–133 Wildgaard K, Ringsted TK, Ravn J, Werner MU, Kehlet H (2013a) Late sensory changes following chest drain insertion during thoracotomy. Acta Anaesthesiol Scand 57(6):776–783 Wildgaard K, Ringsted TK, Kehlet H, Werner MU (2013b) Quantitative sensory testing in patients with postthoracotomy pain syndrome: part 2: variability in thermal threshold assessments.

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Behavioral Neurobiology of Chronic Pain by Bradley K. Taylor, David P. Finn

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