By Joseph J. Stephanos
Addresses the entire gamut of questions in metalloprotein science
Formatted as a question-and-answer advisor, this e-book examines all significant households of steel binding proteins, featuring our most modern knowing in their structural, physicochemical, and practical houses. in addition, it introduces new and rising clinical purposes of metalloproteins. Readers will notice either the underlying chemistry and biology of this significant zone of study in bioinorganic chemistry.
Chemistry of Metalloproteins incorporates a development block process that permits readers to grasp the fundamentals after which improve to extra refined subject matters. The booklet starts with a common advent to bioinorganic chemistry and metalloproteins. subsequent, it covers:
- Alkali and alkaline earth cations
- Copper proteins
- Iron proteins
- Vitamin B12
Chapters are richly illustrated to assist readers appreciate all of the chemical innovations that govern the organic motion of metalloproteins. additionally, every one bankruptcy ends with an inventory of instructed unique learn articles and experiences for extra research of person topics.
Presenting our most present realizing of metalloproteins, Chemistry of Metalloproteins is suggested for college kids and researchers in coordination chemistry, biology, and medicine.
Each quantity of the Wiley sequence in Protein and Peptide technological know-how addresses a particular part of the sphere, reviewing the newest findings and providing a vast diversity of views. The volumes during this sequence represent crucial interpreting for biochemists, biophysicists, molecular biologists, geneticists, phone biologists, and physiologists in addition to researchers in drug layout and improvement, proteomics, and molecular medication with an curiosity in proteins and peptides.
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Additional info for Chemistry of metalloproteins : problems and solutions in bioinorganic chemistry
As principal biological cations with Cl , provide the ionic strength (μ Σ mi zi 2 , where mi is the molality (mol/kg) and z is the charge of positive or negative ions), which deﬁnes: The operating environment for biological macromolecules (proteins, polysaccharides, and nucleic acids) The conformations of these macromolecules 3. , inside vs. outside of cell; Table 2-1): Store energy Transmit information Solvent and Solute Movement through Cell Membrane Why are there different mechanisms for solvent and solute movement through the membrane’s cell, and what are these mechanisms?
22. G. L. , Inorganic Biochemistry, Elsevier, Amsterdam (1973). 23. ,Wiley,London(1981). 24. P. M. Harrison and R. J. Hoare, in Metals in Biochemistry, Chapman and Hall, London and New York (1980). 25. R. J. P. Williams and J. R. R. F. da Silva, in New Trend in Bio-Inorganic Chemistry, Academic, London (1978). 26. C. A. , Techniques and Topic in Bioinorganic Chemistry, Macmillan, London (1975). 01%. The alkali metals have a single s electron in the outer shell with low ionization enthalpies. The chemistry of these metals is of their M+ ions, which have a sphere-shaped and low polarizability.
Stiefel, and J. S. Valentine, in Biological Inorganic Chemistry, University Science Books Sausalito, CA, (2007). 8. H-B. Kraatz and N. Metzler-Nolte, in Concepts and Models in Bioinorganic Chemistry, Wiley, Hoboken, NJ (2006). 9. W. Kaim and B. Schwederski, in Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Wiley, New York (1994). 10. E-I. Ochaia, in Bioinorganic Chemistry: A Survey, Elsevier, San Diego, CA (2008, 2011). 11. R. M. Roat-Malone, in Bioinorganic Chemistry: A Short Course, Wiley-Interscience, Hoboken, NJ (2002).
Chemistry of metalloproteins : problems and solutions in bioinorganic chemistry by Joseph J. Stephanos